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Sickle cell trait in a white Jewish family presenting as splenic infarction at high altitude
Author(s) -
Shalev Oded,
Boylen Alice L.,
Levene Cyril,
Oppenheim Ariella,
Rachmilewitz Eliezer A.
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830270111
Subject(s) - sickle cell trait , splenic infarction , trait , white (mutation) , judaism , medicine , immunology , genetics , biology , disease , gene , history , spleen , archaeology , computer science , programming language
We report the presence of sickle cell trait in several members of a white Jewish family. The trait was discovered when the propositus developed massive splenic infarction at high altitude. No erythrocyte markers characteristic of African ancestry were detected in any of the family members. This is the first bona fide documentation of sickle trait among white Jews.