Premium
Refractory aplastic anemia: Concomitant therapy with antithymocyte globulin and high‐dose corticosteroids
Author(s) -
Pulver Kerry P.,
Flaum Morris A.
Publication year - 1987
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830250110
Subject(s) - concomitant , medicine , refractory (planetary science) , aplastic anemia , globulin , immunology , bone marrow , biology , astrobiology
Bone marrow transplantation is possible for only a minority of patients with severe aplastic anemia. There has been successful treatment in some patients with immunosuppressive agents: high‐dose 6‐methylprednisolone, antilymphocyte globulin, and antithymocyte globulin. We report the successful treatment oftwo patients with severe aplastic anemia with the simultaneous adminstration of antithymocyte globulin and high‐dose 6‐methylprednisolone after failure with antithymocyte globulin and low‐dose corticosteroids.