Premium
Screening for sickle cell trait: The veterans administration national sickle cell program
Author(s) -
Meyer Leo M.,
Adams Junius G.,
Steinberg Martin H.,
Miller Inez E.,
Stokes Norma
Publication year - 1987
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830240413
Subject(s) - sickle cell trait , medicine , sickle cell anemia , hemoglobinopathy , disease , pediatrics , thalassemia , genetic counseling , cell , trait , anemia , genetics , biology , computer science , programming language
Results of the Veterans Administration Sickle Cell Program for a period of 10 years are presented. We screened 370,250 patients; 404,341 attended educational sessions, and 38,347 had individual counseling sessions. Sickle cell trait was present in 6.4% of patients, and HbC trait was present in 1.8%. The clinically significant disorders HbSC disease, sickle cell anemia, and sickle β thalassemia were present in 0.41% of individuals screened. A large number of uncommon variants were detected. The program enhanced the awareness of and the approach to evaluation of hemoglobinopathies.