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Post‐transfusion purpura: A report of five patients and a review of the pathogenesis and management
Author(s) -
Vogelsang Georgia,
Kickler Thomas S.,
Bell William R.
Publication year - 1986
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830210305
Subject(s) - medicine , purpura (gastropod) , platelet , pathogenesis , platelet transfusion , severe bleeding , blood transfusion , surgery , ecology , biology
We report five cases of post‐transfusion purpura. Despite having profound thrombocytopenia, their management consisted only of steriod administration if serious bleeding was present. In one patient without bleeding, no specific therapy was given. This patient recovered uneventfully. Two patients died. One of these died from complicating illnesses rather than bleeding. The other suffered brain death, the result of a ruptured cerebral aneurysm. Four patients were PL A1 negative. The fifth patient had an antibody to an unidentified platelet‐specific antigen.