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Beta 2 microglobulin in multiple myeloma
Author(s) -
Alexanian Raymond,
Barlogie Bart,
Fritsche Herbert
Publication year - 1985
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830200405
Subject(s) - beta 2 microglobulin , multiple myeloma , chemotherapy , creatinine , beta (programming language) , medicine , gastroenterology , oncology , urology , computer science , programming language
Serum beta 2 microglobulin levels (B 2 M) were evaluated before and during chemotherapy in 97 previously untreated patients with multiple myeloma. Pretreatment values were useful in confirming tumor mass grade, and marked reductions following chemotherapy correlated well with the onset of remission. No gain was evident from correcting the B 2 M for the level of serum creatinine. A pretreatment B 2 M value greater than 6 mg/L correlated with a low response rate and was the most important variable that predicted a short survival time.