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Transformation of myeloma into Ph 1 ‐negative CML with plasma cell antigens
Author(s) -
Paletta Elisabeth,
Goldstein Mervyn,
Papenhausen Peter,
Ciobanu Niculae,
Wiernik Peter H.
Publication year - 1985
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830190312
Subject(s) - multiple myeloma , plasma cell myeloma , chronic myelogenous leukemia , antigen , myeloid , myeloid leukemia , leukemia , immunology , plasma cell leukemia , medicine , plasma cell , cancer research
We report a patient in whom Ph 1 ‐negative chronic myelogenous leukemia (CML) developed 15 years after the diagnosis of myeloma. Combined staining of morphologically myeloid elements in the peripheral blood for myeloid and plasmacytoid antigens revealed double‐marker expression, suggesting that the two neoplasms arose from a common originator cell.