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Familial hereditary thrombocytopenia and HLA
Author(s) -
Naparstek Yaakov,
Abrahamov Ayala,
Cohen Tirza,
Brautbar Chaim
Publication year - 1984
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830170203
Subject(s) - human leukocyte antigen , medicine , disease , locus (genetics) , pediatrics , immunology , genetics , antigen , biology , gene
Three generations of a Jewish family with hereditary thrombocytopenia (HT) are described. The disease was manifested clinically by mild bleeding tendency since infancy. Circumcision, however, did not result in excessive bleeding. HLA study in this family indicated that the HT locus is not linked to HLA.