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Absence of platelet activating factor (PAF) mediated platelet aggregation: A new platelet defect
Author(s) -
PelczarWissner Catherine J.,
McDonald Elizabeth G.,
Sussman Ira I.
Publication year - 1984
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830160413
Subject(s) - platelet activating factor , platelet , platelet aggregation , platelet factor 4 , medicine , chemistry , immunology
The failure of normal human platelets to aggregate in response to platelet activating factor (PAF) has not been previously observed. We report here the first case of a patient whose platelets did not aggregate to PAF on multiple occasions.