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Increased prevalence of polycythemia vera in parents of patients on polycythemia vera study group protocols
Author(s) -
Brubaker Leonard H.,
Wasserman Louis R.,
Goldberg Judith D.,
Pisciotta Anthony V.,
McIntyre O. Ross,
Kaplan Manuel E.,
Modan Baruch,
Flannery John,
Harp Rollie
Publication year - 1984
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830160407
Subject(s) - polycythemia vera , medicine , incidence (geometry) , disease , population , pediatrics , gastroenterology , physics , environmental health , optics
An investigation of relatives of 652 patients entered on studies of the Polycythemia Vera Study Group yielded five documented cases of the disease among the parents of patients. When compared with expected values based on the Connecticut Tumor Registry and other population studies a significant increase was found in the lifetime incidence of polycythemia vera in parents of these patients.