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Aging of the erythrocyte. 23. Changes in the permeation of spin‐labeled electrolytes
Author(s) -
Bartosz Grzegorz,
Gwozdzinski Krzysztof
Publication year - 1983
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830140409
Subject(s) - permeation , electrolyte , in vivo , chemistry , red blood cell , biophysics , band 3 , spin label , in vitro , membrane , red cell , erythrocyte membrane , ion , biochemistry , medicine , biology , organic chemistry , electrode , microbiology and biotechnology
Abstract The transport of spin‐labeled anions and cations was studied in bovine erythrocyte fractions of various ages. Permeation of a spin‐labeled anion, 3‐carboxy‐2,2,5,5‐tetramethylpyrrolidine‐1‐oxyl into the cells was found to be significantly slower in older cells, suggesting a functional impairment of the band 3 protein of the erythrocyte membrane during red cell aging in vivo.