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Burkitt cell leukemia with abnormality of chromosome no. 1
Author(s) -
Solomons H. D.,
Mendelow B.,
Levinstein A.,
Johnson A. E.,
Bernstein R.
Publication year - 1983
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830140312
Subject(s) - abnormality , chromosome , chromosome abnormality , leukemia , biology , karyotype , chromosomal abnormality , genetics , cancer research , medicine , gene , psychiatry
Abstract A case of L 3 (Burkitt cell) leukemia with chromosome 1 abnormality but no detectable abnormalities of chromosomes 8 or 14 is reported. This is the first time that L 3 leukemia has been shown to be associated with a primary abnormality of chromosome 1. The implications of these findings relative to the development of B‐cell ALL and the role of chromosome 1 in human neoplasia is discussed.