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Hemoglobin queens: α34 (B15) Leu‐Arg structural and functional properties and its association with Hb E
Author(s) -
MooPenn W. F.,
Jue D. L.,
Johnson M. H.,
McGuffey J. E.,
Simpkins H.,
Katz J.
Publication year - 1982
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830130408
Subject(s) - microcytosis , hemoglobin , vietnamese , hemoglobinopathy , hemoglobin a2 , medicine , biology , anemia , hemolytic anemia , iron deficiency , philosophy , linguistics
Hemoglobin Queens: α34 (B15) Leu‐Arg was found in association with Hb E in a Vietnamese boy. The observed microcytosis and hypochromia were due to Hb E, which also occurred in other members of this family. The functional properties of Hb Queens in the absence and presence of allosteric effectors were normal. The abnormal hemoglobins appear to be unrelated to the hyperbilirubinemia that was observed at birth.