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Thrombotic thrombocytopenic purpura: Recovery after plasmapheresis, corticosteroids, splenectomy, and antiplatelet agents
Author(s) -
Rothberg Harvey,
Pachter Ilana,
Kosmin Martin,
Stevens D. Barton
Publication year - 1982
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830120311
Subject(s) - plasmapheresis , splenectomy , medicine , thrombotic thrombocytopenic purpura , purpura (gastropod) , surgery , platelet , immunology , spleen , antibody , ecology , biology
A 68‐year‐old woman severely ill with thrombotic thrombocytopenic purpura (TTP) made a complete recovery after splenectomy was added to a program of corticosteroids, antiplatelet agents, and plasmapheresis. The authors review the subject of therapy of TTP. They advise high‐dose corticosteroids, antiplatelet agents, and plasmapheresis, with splenectomy to be considered as an effective alternative.