Hypereosinophilia in a monosomy 7 myeloproliferative disorder in childhood | Zendy

Humphrey M. J. | Zendy; Hutter J. J. | Zendy; Tom W. W. | Zendy

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Hypereosinophilia in a monosomy 7 myeloproliferative disorder in childhood

Author(s) -

Humphrey M. J.,

Hutter J. J.,

Tom W. W.

Publication year - 1981

Publication title -

american journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.456

H-Index - 105

eISSN - 1096-8652

pISSN - 0361-8609

DOI - 10.1002/ajh.2830110113

Subject(s) - hypereosinophilia , eosinophilia , monosomy , pathology , myeloproliferative disorders , bone marrow , medicine , etiology , population , immunology , karyotype , biology , genetics , chromosome , environmental health , gene

Hyperosinophilia in association with a monosomy 7 myeloproliferative disorder is described in an eight‐year‐old boy. Antileukemic treatment resulted in a decrease in the eosinophilia, but did not appear to affect the blast cell population or the presence of monosomy 7 cells in the bone marrow. These findings suggest that bone marrow karyotyping may be useful in differentiating pre‐malignant causes of eosinophilia from those with a more benign etiology.

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