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Transfusion‐induced malaria in a splenectomized β‐thalassemia major patient and review of blood donor screening methods
Author(s) -
Joishy Suresh K.,
Lopez Cynthia G.
Publication year - 1980
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830080214
Subject(s) - splenectomy , malaria , medicine , thalassemia , severe malaria , serology , blood transfusion , intensive care medicine , transfusion medicine , pediatrics , immunology , plasmodium falciparum , spleen , antibody
Transfusion‐induced malaria may be a serious threat to the life of a group of special patients: those who require many transfusions, those who have been treated with immunosuppressants, and those who have undergone splenectomy. We describe transfusion‐induced malaria in a β‐thalassemia major patient who had undergone splenectomy. Existing guidelines for screening and excluding donors who have or have had malaria are inadequate, and serologic screenings are too costly. We suggest some guidelines that may help prevent transfusion‐induced malaria and supply an index of suspect signs and symptoms as a key to diagnosis.