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Hemopoietic precursor cells in human peripheral blood
Author(s) -
Niskanen Eero,
Olofsson Tor,
Cline Martin J.
Publication year - 1979
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830070303
Subject(s) - haematopoiesis , stem cell , peripheral blood , induced pluripotent stem cell , in vivo , in vitro , precursor cell , biology , immunology , agar , human blood , blood cell , microbiology and biotechnology , biochemistry , genetics , gene , bacteria , physiology , embryonic stem cell
Human peripheral blood contains two types of stem cells that differentiate along the granulocytic pathway. They are separable by their ability to form colonies in agar in vitro (CFU‐C) and in plasma clots in diffusion chambers in vivo (CFU‐DG). Kinetic studies suggest that CFU‐DG represents an intermediate between the still hypothetical human pluripotent stem cell and CFU‐C.