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Proliferative function of cadaveric bone marrow cells
Author(s) -
Liu Paul L.,
Ogawa Makio,
Crook Lynn,
Ochia Roland,
Upshur Jane K.
Publication year - 1978
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830050210
Subject(s) - cadaveric spasm , haematopoiesis , bone marrow , biology , spleen , pathology , stem cell , induced pluripotent stem cell , immunology , medicine , anatomy , microbiology and biotechnology , gene , genetics , embryonic stem cell
The proliferative function of human and murine cadaveric bone marrow was studied using methylcellulose clonal cell culture assays and the murine spleen colony technique. The study revealed persistence of hemopoietic functions for as long as 19 postmortem hours in cadaveric marrows of some patients. Studies of murine cadaveric marrows corresponded with those of human marrows. These results strongly suggest that human pluripotent hemopoietic stem cells survive in cadaveric marrows.