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The distinctive features of acute monocytic leukemia
Author(s) -
Shaw Michael T.
Publication year - 1978
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830040113
Subject(s) - acute monocytic leukemia , acute leukemia , cytochemistry , leukemia , medicine , monocytic leukemia , pathology , acute megakaryoblastic leukemia , immunology , ultrastructure
Acute monocytic leukemia is an uncommon form of acute leukemia. Distinctive clinical features include gingival hypertrophy, lymphoadenopathy, coagulation disorders, and lysozymuria. Blast cell morphology and cytochemistry are diagnostic. Receptors for the Fc fragment of IgG have been demonstrated on the basis of a few cases. The drug VP 16–213 has been shown to be very effective in treatment of untreated and previously treated patients.