Premium
Increase in platelet aggregation following a rise in plasma free fatty acids
Author(s) -
Burstein Yoav,
Berns Lawrence,
Heldenberg Dov,
Kahn Yael,
Werbin Ben Zion,
Tamir Israel
Publication year - 1978
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830040104
Subject(s) - heparin , platelet aggregation , platelet , chemistry , medicine , endocrinology , intensity (physics) , negative correlation , positive correlation , fatty acid , biochemistry , physics , quantum mechanics
Platelet aggregation was studied following intravenous injection of heparin to nine healthy adults. Heparin is known to produce an increase in the concentration of free fatty acids (FFA) within 10 minutes of intravenous injection. A significant correlation was found between the intensity of primary platelet aggregation and changes in plasma FFA levels. No correlation was found between plasma FFA levels and the intensity of secondary platelet aggregation.