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Post‐transfusion thrombocytopenic purpura: A case report
Author(s) -
Howard Jean E.,
Glassberg Alan B.,
Perkins Herbert A.
Publication year - 1976
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830010309
Subject(s) - medicine , prednisone , thrombocytopenic purpura , platelet , blood transfusion , purpura (gastropod) , platelet transfusion , antibody , thrombotic thrombocytopenic purpura , surgery , immunology , pediatrics , ecology , biology
Post‐transfusion thrombocytopenic purpura (PTTP) is a rare syndrome which was first brought to widespread attention by Shulman et al. Eighteen cases have been reported. The present report describes an additional patient, a multiparous female who developed petechiae 7 days after blood transfusion. The patient's serum contained anti‐PI A1 antibodies and her own platelets were PI A1 ‐negative. She was treated with prednisone and recovered spontaneously without exchange transfusion of whole blood or plasma.
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