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Identification of Chlamydia trachomatis in a patient with ocular lymphoma
Author(s) -
Contini Carlo,
Seraceni Silva,
Carradori Silvia,
Cultrera Rosario,
Perri Paolo,
Lanza Francesco
Publication year - 2009
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.21477
Subject(s) - chlamydia psittaci , psittacosis , chlamydia trachomatis , doxycycline , chlamydia , chlamydiaceae , pathogen , chlamydiales , antibiotics , chlamydophila pneumoniae , lymphoma , biology , immunology , virology , microbiology and biotechnology , medicine
Accumulating evidence suggests that infectious agents may play a role in ocular adnexa lymphomas (OALs) of MALT-type [1-4]. In particular, Chlamydia psittaci, the causative agent of psittacosis, has been detected by PCR in most patients from Italy or isolated eastern Asiatic countries with OALs in absence of other Chlamydia species [4-8]. These patients have also been shown to have a complete or partial response to doxycycline, recognized to be a cheap and safe treatment in these patients [5,6]. In contrast, OAL patients from other geographic areas and with different genetic background were found to be negative for C. psittaci DNA or had a quite variable response to antibiotic treatment, assuming that this pathogen might not play a ubiquitous role in OALs and that bacterial infection is not associated with OAL [8-12].