Premium
Cryopreservation of hematopoietic stem cells
Author(s) -
Berz David,
McCormack Elise M.,
Winer Eric S.,
Colvin Gerald A.,
Quesenberry Peter J.
Publication year - 2007
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20707
Subject(s) - stem cell , cryopreservation , cord blood , haematopoiesis , transplantation , hematopoietic stem cell transplantation , medicine , biology , immunology , surgery , microbiology and biotechnology , embryo
Stem cell transplantation represents a critical approach for the treatment of many malignant and non‐malignant diseases. The foundation for these approaches is the ability to cryopreserve marrow cells for future use. This technique is routinely employed in all autologous settings and is critical for cord blood transplantation. A variety of cryopreservatives have been used with multiple freezing and thawing techniques as outlined in the later chapters. Freezing efficiency has been proven repeatedly and the ability of long‐term stored marrow to repopulate has been established. Standard approaches outlined here are used in many labs as the field continues to evolve. Am. J. Hematol., 2007. © 2007 Wiley‐Liss, Inc.