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Sweet's syndrome in chronic lymphocytic leukemia associated with neutropenic fever and granulocyte colony stimulation factor
Author(s) -
Thompson Michael A.,
Dyson Senait W.,
Faderl Stefan
Publication year - 2006
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20666
Subject(s) - medicine , granulocyte colony stimulating factor , sweet's syndrome , chronic lymphocytic leukemia , granulocyte , sepsis , immunology , leukemia , chemotherapy , stimulation , neutropenia
Abstract Granulocyte colony stimulation factor (G‐CSF) is commonly used in the treatment of chemotherapy‐induced myelosuppression. We report the case of a 62‐year‐old man with chronic lymphocytic leukemia who presented with neutropenic fever and sepsis. After treatment with G‐CSF he developed Sweet's syndrome. Sweet's syndrome is a rare disorder but has been associated with cancer recurrence as well as administration of G‐CSF. We present clinical and pathologic images that highlight the salient features of this entity. Am. J. Hematol., 2006. © 2006 Wiley‐Liss, Inc.