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Dural venous sinus thrombosis in a patient with sickle cell disease: Case report and literature review 1
Author(s) -
Ciurea S.O.,
Thulborn K.R.,
Gowhari M.
Publication year - 2006
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20573
Subject(s) - medicine , thrombosis , magnetic resonance imaging , dural venous sinuses , cerebral venous sinus thrombosis , venous thrombosis , surgery , sigmoid sinus , magnetic resonance angiography , intracranial thrombosis , venography , heparin , radiology
We report a case of dural venous sinus thrombosis (DVST) in a patient who developed seizures following exchange transfusion for treatment of acute chest syndrome associated with sickle cell disease. Evaluation with magnetic resonance imaging and magnetic resonance venography of the brain indicated left sigmoid sinus thrombosis. The history and laboratory evaluation did not reveal any other inherited or acquired hypercoagulable states. This is the fourth case of dural venous sinus thrombosis associated with sickle cell disease reported in literature. The patient had a favorable outcome with early treatment of unfractionated heparin. Am. J. Hematol. 81:290–293, 2006. © 2006 Wiley‐Liss, Inc.