Echinocytosis—An unusual manifestation of hemangioma

The case of a 21 year‐old female with echinocytosis and a littoral cell hemangioma is reported. The patient had no significant past medical history and presented with abdominal pain and splenomegaly. A large percentage of echinocytes were noted on her peripheral smear in the absence of any known causes. A CT‐recognized splenic mass led to splenectomy and a benign hemangioma was found. Red blood cell abnormalities resolved immediately after the surgery. This is the first case reported in the literature of echinocytosis as a consequence of a hemangioma. Am. J. Hematol. 81:532–534, 2006. © 2006 Wiley‐Liss, Inc.