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Non‐Hodgkin disease in β‐thalassemia major
Author(s) -
Otrock Zaher K.,
Shamseddine Ali I.,
Taher* Ali T.
Publication year - 2006
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20463
Subject(s) - thalassemia , medicine , malignancy , disease , lymphoma , anemia , pediatrics , hemoglobinopathy , hodgkin lymphoma , beta thalassemia
Thalassemia is a spectrum of diseases characterized by the decrease or absence of globin chains. The occurrence of lymphoma in thalassemia has rarely been reported, and our review of the English literature revealed only four cases. Because anemia is always masked by regular transfusions in thalassemic patients, physicians discover a hidden malignancy late in the course of the disease. We hereby report the case of a thalassemic patient developing non‐Hodgkin disease and discuss the possibility of a link between the two disease entities. This case is intended to alert physicians of the possibility of a malignancy in thalassemia patients. Am. J. Hematol. 81:62–64, 2006. © 2005 Wiley‐Liss, Inc.