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Bone marrow embolism in sickle cell disease: A review
Author(s) -
Dang Nghia C.,
Johnson Cage,
EslamiFarsani Mahmoud,
Haywood L. Julian
Publication year - 2005
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20348
Subject(s) - medicine , complication , fat embolism , disease , hemoglobinopathy , acute chest syndrome , sickle cell anemia , intensive care medicine , thalassemia , bone marrow , pediatrics , surgery
The fat embolism syndrome is an important complication of patients with sickle cell hemoglobinopathies because of severe morbidity and mortality. Our recent experience with three cases that survived with intensive supportive care and prompt use of transfusion stimulates this review. A high index of suspicion, prompt use of diagnostic tools, and aggressive clinical management are the keys to a successful outcome. Am. J. Hematol. 79:61–67, 2005. © 2005 Wiley‐Liss, Inc.