Premium
Successful use of recombinant factor VIIa for emergency fasciotomy in a patient with hemophilia A and high‐titer inhibitor unresponsive to factor VIII inhibitor bypassing activity
Author(s) -
Watts Raymond G.
Publication year - 2005
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20314
Subject(s) - recombinant factor viia , medicine , fasciotomy , factor viia , titer , coagulopathy , surgery , forearm , coagulation , gastroenterology , adverse effect , immunology , tissue factor , antibody
We report a patient with hemophilia A and high‐titer factor VIII inhibitor who developed compartment syndrome of his forearm following trauma. Emergency fasciotomy was performed. Initial hemostatic treatment with factor VIII inhibitor bypassing activity (FEIBA) was unsuccessful. Bleeding was controlled with recombinant factor VIIa. Am. J. Hematol. 79:58–60, 2005. © 2005 Wiley‐Liss, Inc.