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Potential role of the ventilation and perfusion (V/Q) lung scan in the diagnosis of acute chest syndrome in adults with sickle cell disease
Author(s) -
Kaur Navleen,
Motwani Bharat,
Sivasubramaniam Devaki,
Feldman Lori,
Allen Sandra,
Ferguson Richard,
Shiomoto Gail,
Ansell David,
Westerman Maxwell,
Feldman Lawrence
Publication year - 2004
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.20179
Subject(s) - acute chest syndrome , medicine , chest radiograph , chest pain , radiology , perfusion , perfusion scanning , clinical significance , cardiology , disease , radiography , sickle cell anemia
The current criteria for diagnosing ACS are chest pain and presence of a new infiltrate on the chest radiograph (CXR). This study was designed to evaluate the role of ventilation and perfusion (V/Q) scan to assist in the early diagnosis of ACS. An abnormal V/Q scan was associated with a diagnosis of ACS that reached a statistical significance ( P < 0.038). The sensitivity and specificity were found to be 60% and 100%, respectively. We conclude that V/Q scan may play a role in the early diagnosis of ACS. Am. J. Hematol. 77:407–409, 2004. © 2004 Wiley‐Liss, Inc.