Thalidomide in POEMS syndrome: Case report | Zendy

Sinisalo Marjatta | Zendy; Hietaharju Aki | Zendy; Sauranen Jukka | Zendy; Wirta Ole | Zendy

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Thalidomide in POEMS syndrome: Case report

Author(s) -

Sinisalo Marjatta,

Hietaharju Aki,

Sauranen Jukka,

Wirta Ole

Publication year - 2004

Publication title -

american journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.456

H-Index - 105

eISSN - 1096-8652

pISSN - 0361-8609

DOI - 10.1002/ajh.20051

Subject(s) - poems syndrome , organomegaly , thalidomide , medicine , polyneuropathy , ascites , lenalidomide , gastroenterology , pathology , dermatology , immunology , multiple myeloma

We report a patient with incapacitating POEMS syndrome characterized by serum monoclonal protein, polyneuropathy, organomegaly, endocrinopathy, mesangiocapillary glomerulonephritis, massive ascites formation, and pulmonary hypertension. A dramatic improvement in the clinical condition occurred after administration of thalidomide, a drug with known anti‐angiogenetic, anti‐proliferative, and anti‐cytokine properties. Am. J. Hematol. 76:66–68, 2004. © 2004 Wiley‐Liss, Inc.

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