Developing human erythroid cells grown in transferrin‐free medium utilize iron originating from extracellular ferritin | Zendy

Leimberg J.M. | Zendy; Konijn A.M. | Zendy; Fibach E. | Zendy

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Developing human erythroid cells grown in transferrin‐free medium utilize iron originating from extracellular ferritin

Author(s) -

Leimberg J.M.,

Konijn A.M.,

Fibach E.

Publication year - 2003

Publication title -

american journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.456

H-Index - 105

eISSN - 1096-8652

pISSN - 0361-8609

DOI - 10.1002/ajh.10355

Subject(s) - transferrin , ferritin , extracellular , transferrin receptor , chemistry , microbiology and biotechnology , biochemistry , biology

In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;88:3200–3207; Meyron‐Holtz EG, et al. Blood 1999;94:3205–3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin‐free cultures. Am. J. Hematol. 73:211–212, 2003. © 2003 Wiley‐Liss, Inc.

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