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Factor XIII deficiency mistaken for battered child syndrome: Case of “correct” test ordering negated by a commonly accepted qualitative test with limited negative predictive value
Author(s) -
Newman Richard S.,
Jalili Mehrdad,
Kolls Bradley J.,
Dietrich Rosalind
Publication year - 2002
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10225
Subject(s) - medicine , predictive value , test (biology) , pediatrics , blood transfusion , surgery , paleontology , biology
We report herein a case of Factor XIII deficiency that remained undiagnosed until 2 years of age. Part of the delay in diagnosis was a consequence of testing that was performed on a blood sample obtained after plasma transfusion therapy for a life‐threatening bleeding episode. Due to insufficient family follow‐up after discharge from the hospital, the diagnosis was delayed 1 year until the child was rehospitalized and a pre‐transfusion plasma sample was tested. The commonly accepted approach of using only a qualitative test for the diagnosis of factor XIII deficiency is challenged by this case report. Am. J. Hematol. 71:328–330, 2002. © 2002 Wiley‐Liss, Inc.