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Testicular plasmacytoma: Report of a case and review of the literature
Author(s) -
Anghel Gabriel,
Petti Nicola,
Remotti Daniele,
Ruscio Carla,
Blandino Fortunato,
Majolino Ignazio
Publication year - 2002
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10174
Subject(s) - plasmacytoma , medicine , multiple myeloma , radiation therapy , chemotherapy , pathology , immunohistochemistry , rare disease , disease
Plasmacytomas of the testis are rare neoplasias; they may occur as isolated tumors or in concomitance with generalized multiple myeloma. We report the case of a 77‐year‐old man with previous clinical evidence of multiple myeloma involving skin, ribs, and lungs, and initially treated with surgery, radiotherapy, and chemotherapy attaining partial response. Fourteen months after the onset, the patient presented with left testicular enlargement due to plasmacytoma. Immunohistochemical stains showed monoclonal cytoplasmic IgA‐λ in tumour cells; serum M component showed the same immunoglobulin. Following radiotherapy the tumour mass disappeared. Nonetheless, 2 months later while on chemotherapy, disease recurred with progressive increase of skeletal lesions. The patient is currently alive with disease progression 22 months after onset. On the basis of a review of the literature, the clinical significance of testicular myeloma localization is discussed. Am. J. Hematol. 71:98–104, 2002. © 2002 Wiley‐Liss, Inc.