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Cholecystitis as the presenting manifestation of acute myeloid leukemia
Author(s) -
Bloom Stuart H.,
Coad James E.,
Greeno Edward W.,
Ashrani Aneel A.,
Hammerschmidt Dale E.
Publication year - 2002
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10135
Subject(s) - medicine , myeloid leukemia , leukemia , induction chemotherapy , acute cholecystitis , infiltration (hvac) , chemotherapy , gastrointestinal tract , disease , pathology , gallbladder , physics , thermodynamics
We report a case of acute leukemia, which presented as cholecystitis in a previously healthy middle‐aged adult. Leukemic involvement of the gastrointestinal tract is a well‐known clinicopathological entity. However, leukemic infiltration of the gall bladder wall is a rare occurrence. It has only been previously described in the setting of relapsed disease and, to our knowledge, has never been reported as the primary manifestation of de novo acute leukemia. The patient in question was treated with standard induction and consolidation chemotherapy and remains in complete remission 19 months after his presentation with symptoms consistent with cholecystitis. Am. J. Hematol. 70:254–256, 2002. © 2002 Wiley‐Liss, Inc.