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Autoimmune hemolytic anemia in patients infected with human immunodeficiency virus‐1
Author(s) -
Koduri Prasad Rao,
Singa Prema,
Nikolinakos Petros
Publication year - 2002
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10096
Subject(s) - autoimmune hemolytic anemia , medicine , hemolytic anemia , anemia , prednisone , autoantibody , immunology , immunodeficiency , antibody , immune system
Four men were diagnosed with advanced human immunodeficiency virus infection (AIDS) and autoimmune hemolytic anemia (HIV‐AIHA) during the years 1997–2000 at Cook County Hospital, Chicago. All patients presented with the acute onset of severe hemolytic anemia, fever, and splenomegaly. The direct and indirect antiglobulin tests were positive in all, and three patients had mixed warm and cold autoantibody hemolytic anemia. Shortly after admission, two patients died of severe anemia. Two patients responded to prednisone therapy and remain in remission from AIHA for 15 and 30 months, respectively. Am. J. Hematol. 70:174–176, 2002.© 2002 Wiley‐Liss, Inc.