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Severe hypophosphatemia: A rare cause of intravascular hemolysis
Author(s) -
Melvin Jennifer D.,
Watts Raymond G.
Publication year - 2002
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10071
Subject(s) - hyperphosphatemia , hypophosphatemia , hemolysis , medicine , disseminated intravascular coagulation , gastroenterology , phosphate , kidney disease , biochemistry , chemistry
A 3‐year‐old child presented with severe hyperphosphatemia (phosphate 45 mg/dL) secondary to chronic enema use. Following aggressive correction of the hyperphosphatemia, hypophosphatemia ensued (phosphate 1.7 mg/dL). Concurrently, the patient developed severe intravascular hemolysis and RBC morphologic defects. The hemolysis and morphologic defects corrected with return to normal serum phosphate levels. Severe hypophosphatemia is a rare cause of intravascular hemolysis. Am. J. Hematol. 69:223–224, 2002. © 2002 Wiley‐Liss, Inc.
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