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Langerhans cell histiocytosis following childhood acute lymphoblastic leukemia
Author(s) -
Raj Ashok,
Bendon Robert,
Moriarty Thomas,
Suarez Carlos,
Bertolone Salvatore
Publication year - 2001
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.10004
Subject(s) - langerhans cell histiocytosis , medicine , etiology , chemotherapy , histiocytosis , leukemia , lymphoblastic leukemia , pediatrics , pathology , oncology , immunology , disease
Abstract Langerhans cell histiocytosis (LCH) is a clonal proliferation of Langerhans cells of unknown etiology that results in a range of clinical manifestations. LCH has been known to be associated with a variety of malignant diseases. A 7‐year‐old boy was treated for standard‐risk acute lymphoblastic leukemia (ALL) at age 2 years, on a Children's Cancer Group chemotherapy protocol for 3 years and developed LCH 2 years after completion of chemotherapy. The case and a review of literature on the association of LCH and ALL are presented. Am. J. Hematol. 68:284–286, 2001. © 2001 Wiley‐Liss, Inc.