Open AccessUlcerative colitis associated with primary colorectal lymphoma in Taiwan: A tertiary center study
Author(s) -
Lin ChengLu,
Lin ChengKuan,
Leong YewLoong,
Tung ChienChih,
Shun ChiaTung,
Wei ShuChen,
Wong JauMin,
Weng MengTzu
Publication year - 2020
Publication title -
advances in digestive medicine
Language(s) - English
Resource type - Journals
ISSN - 2351-9800
DOI - 10.1002/aid2.13172
Subject(s) - medicine , ulcerative colitis , incidence (geometry) , lymphoma , biopsy , inflammatory bowel disease , gastroenterology , medical record , diarrhea , diffuse large b cell lymphoma , single center , disease , physics , optics
Ulcerative colitis (UC), an inflammatory bowel disease, increases the incidence of colon adenocarcinoma but is rarely complicated by primary colorectal lymphoma (PCL). This study evaluated diagnostic tools and the clinical symptoms, lymphoma type, and outcome of patients with UC who developed PCL. We retrospectively reviewed patient medical records from 1998 to 2018 at a single tertiary center. Three patients were identified; the studied period from UC diagnosis to lymphoma development ranged from 1 year 7 months to 7 years. Patients were aged 40 to 70 years. All patients were men and presented with bloody diarrhea. Two (66.7%) were diagnosed as having diffuse large B‐cell lymphoma through colonoscopic biopsy. Tumor location differed among all patients. Only one patient survived. PCL is rare in patients with UC and can be diagnosed through colonoscopic biopsy or surgical intervention. However, the clinical outcomes of these patients are poor.