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Design of reactive crystallization systems incorporating kinetics and mass‐transfer effects
Author(s) -
Kelkar Vaibhav V.,
Ng Ka M.
Publication year - 1999
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.690450107
Subject(s) - mass transfer , crystallization , kinetics , chemical engineering , chemistry , thermodynamics , materials science , chromatography , engineering , physics , quantum mechanics
A coherent approach for the design of reactive crystallization systems is presented by incorporating reaction and crystallization kinetics, and mass transfer, into an existing equilibrium‐based conceptual design method. A generic model for a well‐mixed crystallizer is developed; it is applicable to reacting systems with any number of components. The reaction, mass‐transfer and dissolution Damköhler numbers, and the nucleation and growth numbers which result from the generic model, represent the relative rates of the individual steps, and their effect on the resulting crystal‐size distribution and the crystallizer productivity is discussed. Estimates are provided for the typical values of the dimensionless numbers. To describe the solubility behavior of solid‐liquid systems, a generalized equation for the isothermal solubility of a solute in the presence of an arbitrary number of other components is presented. The effects of the dimensionless numbers on the process paths are shown on the phase diagrams for systems involving up to four components. The utility of this integrated approach in the design of reactive crystallization systems is discussed using examples involving single and coprecipitation systems, and a salting out crystallization system.