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Mathematical model of mass transport through dispersed‐phase polymer networks
Author(s) -
Varelas Charalambos G.,
Dixon David G.,
Steiner Carol A.
Publication year - 1995
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.690410407
Subject(s) - diffusion , mass transport , phase (matter) , flux (metallurgy) , mass transfer , polymer , fabrication , mass flux , materials science , chemical physics , chemistry , chemical engineering , thermodynamics , mechanics , chromatography , biochemical engineering , physics , composite material , organic chemistry , engineering , medicine , alternative medicine , pathology
Abstract A mathematical model of mass transport through dispersed‐phase networks to be used for the sustained release of drugs or other solutes at steady rates is presented. The drug is assumed to be encapsulated within the dispersed microdomains and transported to the bulk by diffusion across the interface. A drug is released to the surroundings by diffusion through the bulk. The results show that the desired steady flux of a drug to the surroundings may be obtained given appropriate values of structural properties of the network. These properties may be manipulated easily in the fabrication of dispersed‐phase networks reported previously.