A simultaneous transport‐reaction model for controlled drug delivery from catalyzed bioerodible polymer matrices | Zendy

Thombre A. G. | Zendy; Himmelstein K. J. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A simultaneous transport‐reaction model for controlled drug delivery from catalyzed bioerodible polymer matrices

Author(s) -

Thombre A. G.,

Himmelstein K. J.

Publication year - 1985

Publication title -

aiche journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.958

H-Index - 167

eISSN - 1547-5905

pISSN - 0001-1541

DOI - 10.1002/aic.690310509

Subject(s) - orthoester , catalysis , matrix (chemical analysis) , diffusion , polymer , kinetics , chemistry , drug delivery , chemical engineering , combinatorial chemistry , materials science , organic chemistry , chromatography , thermodynamics , engineering , physics , quantum mechanics

A simultaneous diffusion‐reaction model is presented for the analysis of the kinetics of a chemically eroding poly(orthoester) matrix incorporated with a bioactive agent and with a catalyst to promote the erosion. Simulation results are consistent with experimentally observed hollow residuals and provide a basis for analyzing various design options.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research