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Single‐phase chromatography: Solute retardation by ultrafiltration and electrophoresis
Author(s) -
Lee H.L.,
Reis J. F. G.,
Dohner John,
Lightfoot E. N.
Publication year - 1974
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.690200420
Subject(s) - ultrafiltration (renal) , chromatography , chemistry , tube (container) , electrophoresis , phase (matter) , sorbent , analytical chemistry (journal) , materials science , adsorption , composite material , organic chemistry
It is suggested that chromatographic separations can be performed very effectively in the absence of a stationary sorbent phase by using small diameter tubes or tube bundles for the column and segregating the solutes radially into the slower moving fluid near the tube walls. Separation is achieved by differential solute retardation whenever the degree of segregation is different for the various solute species present. An approximate analysis and preliminary experimental studies demonstrate the feasibility of using ultrafiltration through the tube wall to achieve solute separation. Preliminary estimates based on our ultrafiltration analysis also show that segregation by electromigration is very promising for electrically charged solutes.