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Mass transfer in a horizontal rotating cylinder with applications to the oxygenation of blood
Author(s) -
Landino Enrique,
McCreary J. G.,
Thompson W. A.,
Powers J. E.
Publication year - 1966
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.690120123
Subject(s) - oxygenator , cylinder , mechanics , distilled water , mass transfer , mixing (physics) , mechanical engineering , oxygenation , oxygen , materials science , chemistry , engineering , chromatography , anesthesia , physics , cardiopulmonary bypass , medicine , organic chemistry , quantum mechanics
The horizontal rotating cylinder blood oxygenator has been developed to minimize shear, eliminate bubbles, reduce holdup, and provide for rapid change of the controlled temperature of the blood. To aid in the development of this apparatus a detailed mathematical model was formulated. A simplified model was also developed which yielded an analytical expression relating the amount of material transferred between the gas and liquid in the apparatus to operating variables. In developing these models an attempt was made to include a realistic mechanism for oxygen absorption in blood. Preliminary experiments were carried out by absorbing carbon dioxide into distilled water in the horizontal rotating cylinder. These preliminary results were found to be in good agreement with previous theoretical predictions and calculations that indicated that the equipment should be adequate to act as a lung substitute for a dog. When it was employed in this manner during open‐heart surgery, insufficient oxygen was transferred to support the dog. It is concluded that the most probable reason for failure of the horizontal cylinder to act satisfactorily as a blood oxygenator is poor mixing in the blood pool.