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Issue information
Publication year - 2017
Publication title -
aiche journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.15471
Subject(s) - internalization , endosome , citation , computer science , nucleic acid , world wide web , information retrieval , intracellular , computational biology , chemistry , biology , biochemistry , cell
Cover illustration. Intracellular delivery of nucleic acids by poly(beta‐amino ester)s (PBAEs) requires multiple steps, including self‐assembly into nucleic acid‐containing PBAE nanoparticles, cellular internalization, endosomal escape, and cargo release at the target site. These nanoparticles have been used to deliver functional genes to treat brain cancer in novel ways. 10.1002/aic.15698