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Rate constants of mass transfer kinetics in reversed phase liquid chromatography
Author(s) -
Hong Lan,
Gritti Fabrice,
Gulochon Georges,
Kaczmarski Krzysztof
Publication year - 2005
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.10565
Subject(s) - mass transfer , thermal diffusivity , tortuosity , thermodynamics , alkylbenzenes , chemistry , kinetics , particle (ecology) , reaction rate constant , particle size , mass transfer coefficient , constant (computer programming) , phase (matter) , analytical chemistry (journal) , chromatography , porosity , organic chemistry , physics , quantum mechanics , oceanography , computer science , programming language , geology , benzene
The parameters of the kinetics of mass transfer of several n ‐alkylbenzenes were measured by the method of moments on a series of columns prepared with different samples of the same RPLC packing material having widely different average particle diameters, from 3 to 50 μm. These data were analyzed using the available models, and correlations. The best agreement between experimental and theoretical data was obtained under the assumption that the rate constant for the external mass transfer increases with increasing average particle size, an unexpected conclusion. It was also shown that the interpretation of the relative importance of the roles of pore diffusivity and surface diffusivity in the internal mass transfer kinetics is somewhat ambiguous and that the conclusion to be drawn from experimental results depends on the assumptions made regarding the tortuosity model and the relationship between k ext and the average particle size. © 2005 American Institute of Chemical Engineers AIChE J, 2005