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Kinetic model for separation of particle mixtures by interfacial partitioning
Author(s) -
Hoeben M. A.,
van der Lans R. G. J. M.,
van der Wielen L. A. M.,
Kwant G.
Publication year - 2004
Publication title -
aiche journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.958
H-Index - 167
eISSN - 1547-5905
pISSN - 0001-1541
DOI - 10.1002/aic.10105
Subject(s) - adsorption , desorption , chemistry , monolayer , particle (ecology) , partition (number theory) , chemical engineering , langmuir , kinetics , kinetic energy , polar , thermodynamics , chromatography , chemical physics , biochemistry , oceanography , physics , mathematics , combinatorics , quantum mechanics , engineering , geology , astronomy
A mechanistic study is presented on the partition behavior of mixtures of particles in interfacial partitioning with liquid two‐phase systems. A model is developed based on a mechanism of competitive adsorption of particles at the liquid‐liquid interface. In this model, it is assumed that partitioning is the result of a dynamic process of continuous adsorption and desorption of particles at droplet interfaces. It is shown that under certain conditions such a process can be described by means of Langmuir‐type adsorption isotherms. The model is tested with partition data of mixtures of ampicillin and phenylglycine crystals in a water/n‐pentane system, which leads to a reasonable quantitative description. The results indicate that for this particular system, adsorption of crystals at the interface occurs up to amounts that are needed for a monolayer coverage. In case larger amounts of crystals are present, partitioning of particles is subject to a competition for the available interfacial area. In such a case, the kinetics of adsorption and desorption of the particles to the interface seem to differ from a situation where the interface is partly uncovered. © 2004 American Institute of Chemical Engineers AIChE J, 50: 1156–1168, 2004