Open AccessConstruction of fluorescent hyperbranched polysiloxane‐based clusteroluminogens with enhanced quantum yield and efficient cellular lighting
Author(s) -
Bai Tian,
Zhang Yunsheng,
Wang Lan,
Yan Hongxia,
Zhou Wenhao
Publication year - 2023
Publication title -
aggregate
Language(s) - English
Resource type - Journals
ISSN - 2692-4560
DOI - 10.1002/agt2.267
Subject(s) - fluorescence , quantum yield , biocompatibility , conjugated system , luminescence , polymer , materials science , quantum efficiency , photochemistry , yield (engineering) , fluorescence lifetime imaging microscopy , nanotechnology , hydrogen bond , quantum , chemistry , molecule , optoelectronics , organic chemistry , optics , composite material , physics , metallurgy , quantum mechanics
Abstract Owing to its designability and intrinsic fluorescence, non‐conjugated hyperbranched polysiloxane (HBPSi) has attracted widespread attention in biological filed, while it is still severely restricted by low fluorescence efficiency. So, in this paper, we introduced disulfide into HBPSi improving their luminescence properties and synthesized different molecular weight HBPSi (P1, P2, and P3). Surprisingly, P1 exhibited ultrahigh quantum yield up to 47.81%. Meanwhile, experiments applied with theoretical calculations were employed to explore the fluorescence mechanism, which is attributed to efficient restricting of non‐radiative decay by clusteroluminogens formed with the cooperation of hyperbranched structure and double hydrogen bonding. In addition, the biocompatibility of P1 was verified by co‐culture with MC3T3‐E1 and P1 lighted up mouse fibroblast cells without fluorescent dyes. This work designed a novel fluorescent polymer with ultrahigh fluorescence quantum yield and cell imaging ability, which is promising in visualization diagnosis and treatment of tumor.