Open AccessUltrasensitive Detection of Biomarkers in a Color‐Switchable Microcavity‐Reactor Laser (Adv. Sci. 23/2022)
Author(s) -
Li Ran,
Song Zongpeng,
Zhu Haiou,
Zhang Fanglin,
Chen Lingling,
Ning CunZheng,
Ruan Shuangchen
Publication year - 2022
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202270144
Subject(s) - whispering gallery wave , microsphere , materials science , biomarker , laser , optics , multiplexing , optoelectronics , signal (programming language) , detection limit , nanotechnology , chemistry , physics , resonator , computer science , chromatography , telecommunications , biochemistry , chemical engineering , engineering , programming language
Color‐Switchable Microlasers In article number 2202326 by Haiou Zhu, Cun‐Zheng Ning, Shuangchen Ruan, and co‐workers, a permeable color‐switchable whispering‐gallery‐mode (WGM) microlaser for ultrasensitive detection of biomarker is developed. The more sensitive concentration dependence allows even visual distinguishability of small changes in biomarker concentration. Due to the narrow cavity modes and largely shifted spectral peaks, the microlaser output from the microsphere can act as “normal‐abnormal” logic signal to integrate into multiplexing detection assays.