Bile Acid–Microbiome Interaction Promotes Gastric Carcinogenesis (Adv. Sci. 16/2022) | Zendy

Wang Shouli | Zendy; Kuang Junliang | Zendy; Zhang Hongwei | Zendy; Chen Wenlian | Zendy; Zheng Xiaojiao | Zendy; Wang Jieyi | Zendy; Huang Fengjie | Zendy; Ge Kun | Zendy; Li Mengci | Zendy; Zhao Mingliang | Zendy; Rajani Cynthia | Zendy; Zhu Jinshui | Zendy; Zhao Aihua | Zendy; Jia Wei | Zendy

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Bile Acid–Microbiome Interaction Promotes Gastric Carcinogenesis (Adv. Sci. 16/2022)

Author(s) -

Wang Shouli,

Kuang Junliang,

Zhang Hongwei,

Chen Wenlian,

Zheng Xiaojiao,

Wang Jieyi,

Huang Fengjie,

Ge Kun,

Li Mengci,

Zhao Mingliang,

Rajani Cynthia,

Zhu Jinshui,

Zhao Aihua,

Jia Wei

Publication year - 2022

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.202270105

Subject(s) - bile reflux , bile acid , microbiome , cancer research , carcinogenesis , carcinogen , cancer , stat3 , gastroenterology , medicine , reflux , chemistry , signal transduction , bioinformatics , biology , biochemistry , disease

New Strategy for the Prevention of Gastric Cancer Bile reflux can promote gastric carcinogenesis through activation of the IL‐6/JAK1‐STAT3 signaling pathway. Inhibition of STAT3 by cryptotanshinone can alleviate this carcinogenic effect, thus providing a new strategy for the prevention of gastric cancer associated with bile reflux. More details can be found in article number 2200263 by Aihua Zhao, Wei Jia, and co‐workers.

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