Open AccessAcute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities (Adv. Sci. 16/2022)
Author(s) -
Zhang Luwen,
Zhao Qiong,
Cang Hui,
Wang Ziqiang,
Hu Xiaojia,
Pan Ruolang,
Yang Yang,
Chen Ye
Publication year - 2022
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202270101
Subject(s) - myeloid leukemia , mesenchymal stem cell , leukemia , adipogenesis , cancer research , haematopoiesis , stromal cell , chemistry , immunology , stem cell , medicine , biology , microbiology and biotechnology
Acute Myeloid Leukemia In article number 2105811, Yang Yang, Ye Chen, and co‐workers report that acute myeloid leukemia (AML) cells educate regular mesenchymal stromal cells (MSCs) towards an adipogenic differentiation propensity with leukemia promotion capabilities. The fish's gradient colors symbolize the influence of the leukemia cells (in black) and hematopoietic stem cells (in red) on their respective surrounding microenvironments.